Healthcare

Nucleo

Website
Founded 2025Origin source ↗Checked 2026-09-15

Overview

We help oncologists and radiologists extract insights from CT scans to support tumor characterization and treatment.

The hospitals we work with include Stanford Hospital, Cedars-Sinai, UCI Health, and Weill Cornell.

Company description As recorded 2026-11-08

Founders & team

Angelica Iacovelli

Founder/CEO

Angelica Iacovelli is the CEO and co-founder of Nucleo. Previously, she was a researcher at Stanford University, where she worked on cardiovascular modeling, simulating blood flow dynamics using GNNs, LSTMs, and Transformers. The models are now part of NVIDIA’s scientific libraries. She holds BS+MS in Mathematical Engineering from Politecnico di Milano and completed a research exchange at IIT Madras.

Founder profile As recorded 2026-09-15

Luca Pegolotti

Founder/CTO

I am a researcher in Applied Mathematics and AI for healthcare by training. I hold degrees from Politecnico di Milano, Italy (BSc) and EPFL, Switzerland (MSc and PhD), and have conducted research at the Stanford School of Medicine during my PhD and as a Postdoc. Before founding Nucleo, I was part of Apple Health AI, where I worked on physics-informed machine learning. I've published papers on computational methods, cardiovascular system modeling, and AI for medical images and optical sensors.

Founder profile As recorded 2026-09-15
2team members reported
Source-reported As recorded 2026-09-15

Founded 2025 · Source

News & product activity

Sources & observations

Y Combinator

Profile depthverified profile
Website observationwebsite reachable
Last website check2026-11-11
Location · source statedSan Francisco, CA, USA
Pricing evidenceNo pricing page confirmed
Maturity: Not assessed · 3 of 6 areas documented

Source-based assessment · automated evidence rules

The retained text does not establish product availability or customer use.

Maturity is an evidence-based assessment, not a success rating. It may understate the current stage where evidence is limited. Coverage records documented areas, not a complete or independently audited company history.

Stage definitions
independent websitesource corroborationreachable websitedescriptive evidenceclassified market and modelsourced peoplesourced founding year