Healthcare

Alfie

Website

At Alfie, we've built a rigorous virtual medical program based on the top research from Cleveland Clinic and Harvard that allows us to precisely determine which weight loss regimen and (as needed) medications will be most effective for our members in a multimodal approach. We're optimizing exercise/nutrition/medications in complex care pathways lik

Founded 2022Origin source ↗Checked 2026-09-15

Overview

At Alfie, we've built a rigorous virtual medical program based on the top research from Cleveland Clinic and Harvard that allows us to precisely determine which weight loss regimen and (as needed) medications will be most effective for our members in a multimodal approach. We're optimizing exercise/nutrition/medications in complex care pathways like no one else has before.

Our program has been shown to be 2x more effective than standard prescription medication and 5x more effective than habit change alone.

We've raised capital from Goodwater Capital, Nina Capital, Air Force Ventures, and Phoenix Club, and various super angels including the founder of OpenTrons (medical labs automation; have raised $240 mill). Also, we're a Y Combinator graduate.

Company description As recorded 2026-11-08

Founders & team

Previously MIST

Company history As recorded 2026-11-08

Alexander Singh

Founder

Healthcare AI founder and investor. Currently investing in healthcare companies at Yosemite, an oncology focused venture firm. Led Alfie (LLM CDS for metabolic health, YC W22) to acquisition by knownwell and formerly built MIST Health (CV spinal diagnostics). Also spent time as an Investment Partner at Pioneer Fund and technology consultant at the FDA during the COVID pandemic.

Founder profile As recorded 2026-09-15
6team members reported
Source-reported As recorded 2026-09-15

Founded 2022 · Source

News & product activity

Sources & observations

Y Combinator

Profile depthverified profile
Website observationwebsite unreachable
Last website check2026-11-11
Location · source statedNew York City, NY, USA; New York, NY, USA
Pricing evidenceNo pricing page confirmed
Maturity: Not assessed · 3 of 6 areas documented

Source-based assessment · automated evidence rules

The source reports an inactive or acquired company; current product identity needs review.

Maturity is an evidence-based assessment, not a success rating. It may understate the current stage where evidence is limited. Coverage records documented areas, not a complete or independently audited company history.

Stage definitions
independent websitesource corroborationdescriptive evidenceclassified market and modelsourced peoplesourced founding year